Choose Synolis

for your patients suffering from Osteoarthritis Joint Pain

Synolis is a patented injectable gel containing Hyaluronic Acid and Sorbitol that has the same rheological properties like a healthy joint fluid. 11

Clinical data demonstrates significant pain relief within the first week after treatment with Synolis, with effects lasting up to 6 months. 1

Flexible Treatment Protocol with 2ml (Multishot) or 4ml (Monoshot) syringe
Gel that has the same properties as a healthy synovial fluid with a cross-over frequency of 0.4Hz
Unique Combination of 2% non-animal origin Hyaluronic Acid & 4% Sorbitol
High-Molecular weight HA of 2mDA

Why 2%
Hyaluronic Acid

High Lubrication11

Better Shock Absorbance11

Restoration of the properties of a healthy synovial fluid11

Why 4% Sorbitol

Sorbitol is an agent which protects Hyaluronic Acid against degradation allowing the preservation of its viscosity and elasticity

Learn more about Aptissen
the swiss company behind Synolis

Key Numbers

Clinical performance

Based on a study of 80mg hyaluronic acid – 160 mg sorbitol on articular pain and mobility associated with gonarthrosis. Results from 93 patients.

Source: Cortet, B., Lombion, S., Naissant, B. et al. Non-Inferiority of a Single Injection of Sodium Hyaluronate Plus Sorbitol to Hylan G-F20: A 6-Month Randomized Controlled Trial. Advances in Therapy 38, 2271–2283 (2021). Read article

61.8 %
of pain relief at 6 months1
78.8 %
of strict responders after 6 months1
89.2 %
of patients were satisfied at the 6 month mark1
53.0 %
reduction on the WOMAC Stiffness scale at 1 month1


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Extend The Life
Of The Natural Joint

How it works