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SYNOLIS | Designed for your movements›Healthcare Professional

Choose Synolis

for your patients suffering from Osteoarthritis Joint Pain

Synolis is a patented injectable gel containing Hyaluronic Acid and Sorbitol that has the same rheological properties like a healthy joint fluid. 11

Clinical data demonstrates significant pain relief within the first week after treatment with Synolis, with effects lasting up to 6 months. 1

Flexible Treatment Protocol with 2ml (Multishot) or 4ml (Monoshot) syringe
Gel that has the same properties as a healthy synovial fluid with a cross-over frequency of 0.4Hz
Unique Combination of 2% non-animal origin Hyaluronic Acid & 4% Sorbitol
High-Molecular weight HA of 2mDA

Why 2%
Hyaluronic Acid

High Lubrication11

Better Shock Absorbance11

Restoration of the properties of a healthy synovial fluid11

Why 4% Sorbitol

Sorbitol is an agent which protects Hyaluronic Acid against degradation allowing the preservation of its viscosity and elasticity

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Learn more about Aptissen
the swiss company behind Synolis

Key Numbers

Clinical performance

Based on a study of 80mg hyaluronic acid – 160 mg sorbitol on articular pain and mobility associated with gonarthrosis. Results from 93 patients.

Source: Cortet, B., Lombion, S., Naissant, B. et al. Non-Inferiority of a Single Injection of Sodium Hyaluronate Plus Sorbitol to Hylan G-F20: A 6-Month Randomized Controlled Trial. Advances in Therapy 38, 2271–2283 (2021). Read article

61.8 %
of pain relief at 6 months1
78.8 %
of strict responders after 6 months1
89.2 %
of patients were satisfied at the 6 month mark1
53.0 %
reduction on the WOMAC Stiffness scale at 1 month1

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Find out more about publications with Synolis

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Monograph

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Extend The Life
Of The Natural Joint

How it works