Choose Synolis
for your patients suffering from Osteoarthritis Joint Pain
Synolis is a smart injectable gel containing Hyaluronic Acid and Sorbitol that acts just like a young, healthy joint fluid.
Clinical data demonstrates significant pain relief within the first week after treatment with Synolis, with effects lasting up to 6 months. 1
Flexible Treatment Protocol with 2ml (Multishot) or 4ml (Monoshot) syringe
Gel that has the same properties as a young and healthy synovial fluid with a cross-over frequency of 0.4Hz
Unique Combination of 2% non-animal origin Hyaluronic Acid & 4% Sorbitol
High-Molecular weight HA of 2mDA
Why 2%
Hyaluronic Acid
High Lubrification
Better Shock Absorbance
Restoration of the properties of a young and healthy synovial fluid
Why 4% Sorbitol
Strong endogenous antioxidant
Protection of Hyaluronic Acid against Degradation
Preservation of Viscosity and Elasticity
Learn more about Aptissen
the swiss company behind Synolis
Key Numbers
Clinical performance
Based on a study of 80mg hyaluronic acid – 160 mg sorbitol on articular pain and mobility associated with gonarthrosis. Results from 93 patients.
Source: Cortet, B., Lombion, S., Naissant, B. et al. Non-Inferiority of a Single Injection of Sodium Hyaluronate Plus Sorbitol to Hylan G-F20: A 6-Month Randomized Controlled Trial. Advances in Therapy 38, 2271–2283 (2021). Read article
61.8
%
of pain relief at 6 months
78.8
%
of strict responders after 6 months
89.2
%
of patients were satisfied at the 6 month mark
53.0
%
reduction on the WOMAC Stiffness scale at 1 month
